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4.2. Neurodegenerative Disease: Treatment and Prevention

Now that you understand the biology of neurodegenerative disease, let’s pivot to a conversation around the topic you care most about: prevention and treatment. We explain how we think about risk reduction regarding Alzheimer’s disease. As with all the horsemen, there is no way to guarantee these things won’t happen. There are, however, science-based tools and approaches you can use to maximize your chances of avoiding these devastating diseases.
Additional Resources
Dive Deeper
A hidden blockbuster drug for Alzheimer’s disease?
Alzheimer’s prevention and the most important thing
Q&A on Alzheimer’s disease drug therapy with Dr. Richard Isaacson
Peter on Alzheimer’s disease prevention and the latest on APOE4
Alzheimer’s disease and glucose metabolism
Can treating hearing loss improve cognitive trajectories and reduce dementia risk?
Non-caffeine components of coffee and their effects on neurodegenerative diseases
Can an annual flu vaccine reduce your risk of Alzheimer’s disease?
Adding context to the Alzheimer’s disease research fraud charges
Low LDL cholesterol and neural development
Does low cholesterol cause cognitive impairment? Part I
Does low cholesterol cause cognitive impairment? Part II
Why the APOE4 allele increases the risk of Alzheimer’s disease, and the connection to blood lipids | Ep. #255 – John Kastelein, M.D., Ph.D.
Diagnosing Alzheimer’s disease | AMA #46 – Peter Attia
Biomarkers for Alzheimer’s disease, the C2N test, and other tools for diagnosis | AMA #46 – Peter Attia
Genetic component of Alzheimer’s disease: genes that confer risk | AMA #46 – Peter Attia
Understanding your APOE status and why it’s important to know | AMA #46 – Peter Attia
The prevalence of Alzheimer’s disease and other forms of dementia, and who is at higher risk | AMA #46 – Peter Attia
Can the risk of Alzheimer’s disease be decreased with behavioral changes? | AMA #46 – Peter Attia
Overview of modifiable behaviors that potentially play a role in risk reduction of neurodegeneration | AMA #46 – Peter Attia
Things that clearly impact brain health: smoking, alcohol, sleep, head injuries, blood pressure, and more | AMA #46 – Peter Attia
How nutrition impacts brain health: common diets, metabolic health, energy balance, and more | AMA #46 – Peter Attia
Comparing common diets: data showing the association between the incidence of Alzheimer’s disease and specific diets | AMA #46 – Peter Attia
Supplements: EPA and DHA, vitamin D, and B vitamins | AMA #46 – Peter Attia
Supplements: theracurmin, cocoa flavonols, and magnesium L-threonate | AMA #46 – Peter Attia
Impact of exercise on brain health, minimum effective dose, and the most important types of exercise | AMA #46 – Peter Attia
Challenging the mind with brain games—does it impact neurodegeneration? | AMA #46 – Peter Attia
The data on sauna and brain health | AMA #46 – Peter Attia
Oral health and its association with brain health | AMA #46 – Peter Attia
How reducing lipids can improve brain health and prevent neurodegeneration | AMA #46 – Peter Attia
The potential impact of hearing loss on brain health and neurodegeneration | AMA #46 – Peter Attia
Alzheimer’s prevention | Ep. #18 – Richard Isaacson, M.D.
Alzheimer’s disease prevention—patient and doctor perspectives | Ep. #138 – Lauren Miller Rogen and Richard Isaacson, M.D.
Cognitive decline, neurodegeneration, and head injuries: mitigation and prevention strategies, supplements, and more | Ep. #257 – Tommy Wood, M.D., Ph.D.
Latest insights on Alzheimer’s disease, cancer, exercise, nutrition, and fasting | Ep. #252 – Rhonda Patrick, Ph.D.