earlymedical2.3. A Patient Conversation: Understanding your Genetic Inheritance
As discussed in the previous lesson, your genetic legacy is one of the primary inputs into your personalized longevity risk profile. By reflecting on your family history, we can gain a finer-grained understanding of the risks most likely to impact your journey. No genetic test can replace the utility of knowing about the health history of those closest to you: your siblings, parents, aunts, uncles, and grandparents.
Additional Resources
Dive Deeper
Genetics: testing, therapy, editing, association with disease risk, autism, and more | Ep. #268 Wendy Chung, M.D., Ph.D. Listen to podcast
The history of the cell, cell therapy, gene therapy, and more | Ep. #244 Siddhartha Mukherjee Listen to podcast
Defining the term “genetics” and why it’s important | AMA #50 – Peter Attia Listen More
What is DNA, and how does it impact our biology and traits? | AMA #50 – Peter Attia Listen More
How are genetics passed down from parent to child? | AMA #50 – Peter Attia Listen More
How much do genes vary across individuals? | AMA #50 – Peter Attia Listen More
Which traits are determined by genetics versus experience or environmental factors? | AMA #50 – Peter Attia Listen More
Reasons for genetic testing | AMA #50 – Peter Attia Listen More
What exactly is being measured by a genetic test? | AMA #50 – Peter Attia Listen More
Testing for monogenic disorders | AMA #50 – Peter Attia Listen More
Understanding polygenic risk | AMA #50 – Peter Attia Listen More
Is genetic testing more important for someone who doesn’t know their family history? | AMA #50 – Peter Attia Listen More
What does it mean to be positive for a particular variant? | AMA #50 – Peter Attia Listen More
What does it mean to be negative for a particular variant? | AMA #50 – Peter Attia Listen More
How does someone get genetic testing through their healthcare provider, and how are these tests performed? | AMA #50 – Peter Attia Listen More
Could having a risk allele for a disease result in an increase in one’s insurance premium? | AMA #50 – Peter Attia Listen More
Other risks associated with genetic testing | AMA #50 – Peter Attia Listen More
How do commercial, direct-to-consumer genetic tests compare to the information one might receive from clinical genetic testing? | AMA #50 – Peter Attia Listen More
Are certain direct-to-consumer tests better than others? | AMA #50 – Peter Attia Listen More
How long until whole genome sequencing becomes genuinely useful? | AMA #50 – Peter Attia Listen More
Final thoughts and advice regarding genetic testing | AMA #50 – Peter Attia Listen More